A chalazion is most closely associated with obstruction of which glands?

A chalazion is most closely associated with obstruction of which glands?

• A. Meibomian glands
• B. Glands of Zeiss
• C. Glands of Moll
• D. Lacrimal gland

Answer: (A)

Chalazion arises when the lipid-secreting Meibomian glands in the eyelid become obstructed. These glands (in the tarsal plates) produce the oily component of the tear film. When a duct is blocked, secretions accumulate and trigger a chronic granulomatous inflammatory reaction, forming a painless, firm nodule inside the eyelid. This contrasts with infections of glands at the lash margin (Glands of Zeiss and Moll) that cause external styes, and with lacrimal gland issues that affect tear production rather than producing a lid lump. So obstruction of the Meibomian glands best explains a chalazion.

Chalazion arises when the lipid-secreting Meibomian glands in the eyelid become obstructed. These glands (in the tarsal plates) produce the oily component of the tear film. When a duct is blocked, secretions accumulate and trigger a chronic granulomatous inflammatory reaction, forming a painless, firm nodule inside the eyelid. This contrasts with infections of glands at the lash margin (Glands of Zeiss and Moll) that cause external styes, and with lacrimal gland issues that affect tear production rather than producing a lid lump. So obstruction of the Meibomian glands best explains a chalazion.