Which sign is NOT typical of contact lens solution toxicity/hypersensitivity?

Which sign is NOT typical of contact lens solution toxicity/hypersensitivity?

• A. Diffuse SPK
• B. Diffus e conjunctival injection
• C. Cobblestone papillae
• D. Follicular conjunctivitis

Answer: (C)

Signs of contact lens solution toxicity or hypersensitivity typically involve widespread surface inflammation from chemical exposure: diffuse corneal epithelial involvement (diffuse SPK) and diffuse conjunctival redness are common. A reactive conjunctival response can also present as follicular conjunctivitis from the immune reaction to preservatives in the solution. Cobblestone papillae, on the other hand, reflect giant papillary conjunctivitis due to chronic mechanical irritation from lenses or deposits on the lens—more about physical irritation than a direct chemical toxicity. So cobblestone papillae are not typical of solution toxicity/hypersensitivity.

Signs of contact lens solution toxicity or hypersensitivity typically involve widespread surface inflammation from chemical exposure: diffuse corneal epithelial involvement (diffuse SPK) and diffuse conjunctival redness are common. A reactive conjunctival response can also present as follicular conjunctivitis from the immune reaction to preservatives in the solution. Cobblestone papillae, on the other hand, reflect giant papillary conjunctivitis due to chronic mechanical irritation from lenses or deposits on the lens—more about physical irritation than a direct chemical toxicity. So cobblestone papillae are not typical of solution toxicity/hypersensitivity.